The mar regulon: multiple resistance to antibiotics and other toxic chemicals.
نویسندگان
چکیده
The chromosomal multiple antibiotic resistance (mar) locus of Escherichia coli and other members of the Enterobacteriaceae controls resistance to multiple, structurally unrelated compounds including antibiotics, household disinfectants, organic solvents and other toxic chemicals. The Mar phenotype is induced following exposure to a variety of chemicals with aromatic rings.
منابع مشابه
Regulation of chromosomally mediated multiple antibiotic resistance: the mar regulon.
Multidrug resistance in bacteria is generally attributed to the acquisition of multiple transposons and plasmids bearing genetic determinants for different mechanisms of resistance (48, 62). However, descriptions of intrinsic mechanisms that confer multidrug resistance have begun to emerge. The first of these was a chromosomally encoded multiple antibiotic resistance (mar) locus (Fig. 1) in Esc...
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ورودعنوان ژورنال:
- Trends in microbiology
دوره 7 10 شماره
صفحات -
تاریخ انتشار 1999